doo wop quiz

March 26th, 2010 Comments Off

Doo Wop Quiz

Thirty great memories about music that caused our parents and teachers grief!

Take the quiz and see how you score as a true ”Oldies Fan.”
Write down your answers and check them against the answers at the end.

(Answers Below)

NOW, DON’T CHEAT!

1. When did ”Little Suzie” finally wake up?

(a) The movie’s over, it’s 2 o’clock
(b) The movie’s over, it’s 3 o’clock
(c) The movie’s over, it’s 4 o’clock

2. ”Rock Around The Clock” was used in what movie?

(a) Rebel Without A Cause

(b) Blackboard Jungle
(c) The Wild Ones

3. What’s missing from a Rock & Roll standpoint? Earth _____

(a) Angel
(b) Mother
(c) Worm

4. ”I found my thrill …..” where?

(a) Kansas City
(b) Heartbreak Hotel
(c) Blueberry Hill

5. ”Please turn on your magic beam, _____ _____ bring me a dream,”:

(a) Mr. Sandman
(b) Earth Angel
(c) Dream Lover

6. For which label did Elvis Presley first record?

(a) Atlantic
(b) RCA
(c) Sun

7. He asked, ”Why’s everybody always pickin’ on me?’’ Who was he?

(a) Bad, Bad Leroy Brown
(b) Charlie Brown
(c) Buster Brown

8. In Bobby Darin’s ”Mack The Knife,” the one with the knife, was named:

(a) Mac Heath
(b) Mac Cloud
(c) McNamara

9. Name the song with ”A-wop bop a-loo bop a-lop bam boom.”

(a) Good Golly, Miss Molly
(b) Be-Bop-A-Lula
(c) Tutti Fruitti

10. Who is generally given credit for originating the term ”Rock And Roll”?

(a) Dick Clark
(b) Wolfman Jack
(c) Alan Freed

11. In 1957, he left the music business to become a preacher:

(a) Little Richard
(b) Frankie Lymon
(c) Tony Orlando

12. Paul Anka’s ”Puppy Love” is written to what star?

(a) Brenda Lee
(b) Connie Francis
(c) Annette Funicello

13. The Everly Brothers are……

(a) Pete and Dick
(b) Don and Phil
(c) Bob and Bill

14. The Big Bopper’s real name was:

(a) Jiles P. Richardson
(b) Roy Harold Scherer Jr.
(c) Marion Michael Morrison

15. In 1959, Berry Gordy, Jr., started a small record company called…

(a) Decca
(b) Cameo
(c) Motown

16. Edd Brynes had a hit with ”Kookie, Kookie, Lend Me Your Comb”. What TV show was he on?

(a) 77 Sunset Strip
(b) Hawaiian Eye
(c) Surfside Six

17. In 1960, Bobby Darin married:

(a) Carol Lynley
(b) Sandra Dee
(c) Natalie Wood

18. They were a one hit wonder with ”Book Of Love’’:

(a) The Penguins
(b) The Monotones
(c) The Moonglows

19. The Everly Brothers sang a song called ”Till I ______ You.”

(a) Loved
(b) Kissed
(c) Met

20. Chuck Berry sang ”Oh, ___________, why can’t you be true?”

(a) Suzie Q
(b) Peggy Sue
(c) Maybelline

21. ”Wooly _______’’

(a) Mammoth
(b) Bully
(c) Pully

22. ”I’m like a one-eyed cat . . . ..”

(a) can’t go into town no more
(b) sleepin’ on a cold hard floor
(c) peepin’ in a seafood store

23. ”Sometimes I wonder what I’m gonna do”

(a) cause there ain’t no answer for a life without booze
(b) cause there ain’t no cure for the summertime blues
(c) cause my car’s gassed up and I’m ready to cruise

24. ”They often call me Speedo, but my real name is ….’

(a) Mr. Earl
(b) Jackie Pearl
(c) Milton Berle

25. ”You’re my Fanny and nobody else’s …..”

(a) girl
(b) butt
(c) love

26. ”I want you to play with my . . . ‘‘

(a) heart
(b) dreams
(c) ding a ling

27. ”Be Bop A Lula ….”

(a) she’s got the rabies
(b) she’s my baby
(c) she loves me, maybe

28. ”Fine Love, Fine Kissing ….”

(a) right here
(b) fifty cents
(c) just for you

29. ”He wore black denim trousers and . . .’’

(a) a pink carnation
(b) pink leotards
(c) motorcycle boots

30. ”I got a gal named . . .”

(a) Jenny Zamboni
(b) Gerri Mahoney
(c) Boney Maroney

Answers:

Scroll Down so you aren’t tempted to cheat

(as if cheating were needed here).

* * * * * * * * * * * *

1 (c) The movie’s over, it’s 4 o’clock
2. (b) Blackboard Jungle
3. (a) Angel
4. (c) Blueberry Hill
5. (a) Mr. Sandman
6. (c) Sun
7. (b) Charlie Brown
8. (a) Mac Heath
9. (c) Tutti Fruitti
10. (c) Alan Freed
11. (a) Little Richard
12. (c) Annette Funicello
13. (b) Don and Phil
14. (a) Jiles P. Richardson
15. (c) Motown
16. (a) 77 Sunset Strip
17. (b) Sandra Dee
18. (b) The Monotones
19. (b) Kissed
20. (c) Maybelline
21. (b) Bully
22. (c) peepin’ in a seafood store
23. (b) cause there ain’t no cure for the summertime blues
24. (a) Mr. Earl
25. (b) butt
26. (c) ding a ling
27. (b) she’s my baby
28. (a) right here
29. (c) motorcycle boots
30. (c) Boney Maroney

Forward to everyone lucky enough

to be teenagers in the Doo Wop Era.
________

ROCK ON!

State and Local Public Officials Mercury-Free Caucus

316 F St., N.E., Suite 210-B

Washington DC 20002

March 24, 2010

Joshua Sharfstein, M.D. Principal Deputy Commissioner

U.S. Food and Drug Administration –

via e-mail JMSharf1@fda.hhs.gov and fax 301-847-3531

Re: FDA should not try to block state and local amalgam fact sheet laws

Dear Deputy Commissioner Sharfstein:

We regret that last year the Food and Drug Administration chose to adopt a rule allowing amalgam to be sold without even informing dental patients and parents that it is mainly mercury. Fortunately, legislatures in several states and some city councils feel otherwise, and have mandated fact sheets be distributed so dental patients and parents will know about the mercury and know they have alternatives such as resin.

We understand you are writing a letter to the City of Philadelphia about its fact sheet.

We urge you to respect the right of states and political subdivisions to write consumers protection laws that differ from your personal views about disclosure. Any effort by FDA to block state legislatures and city councils from making disclosures about amalgam continues to take our country down the wrong path, and may be of questionable legality. Instead, we urge you to focus on rewriting the rule you adopted last year.

Sincerely,

Hon. Daylin Leach, State Senator, Pennsylvania

Hon. Blondell Reynolds Brown, Councilwoman, Philadelphia (author, Philadelphia

amalgam fact sheet ordinance)

Hon. Jay Goyal, State Representative, Ohio

Hon. Michael J. London, Councilman, Trumbull, Connecticut

Hon. Marvin L. Van Haaften, former Director, Iowa Governor’s Office of

Drug Control Policy (“Drug Czar”); and former Sheriff, Marion County, Iowa

Hon. Ann Clifton, RN, BSN, former Assessor, Thurston County, WA

Hon. Charles G. Brown, former Attorney General, West Virginia

Hon. Ron King, DDS, former Member, Minnesota Board of Dentistry

Hon. Kevin Biggers, former Member, Dental Board of California

Hon. Chester L. Yokoyama, DDS, former Member, Dental Board of California

In response to an article written by Delta Dental about why NJ children have the worst teeth in the nation, this is what I responded with: According to the article you wrote, at http://www.nj.com/helpinghands/deltadental/index.ssf/2010/03/new_jersey_ranks_lowest_in_nat.html your answer to the problem is the lack of fluoridation of NJ water. Show me studies where the decay rate went down due to fluoridation. I’d like to open your eyes to the problems that fluoride causes. Please follow the links from the fluoridation page of my website. Be sure to visit fluoridealert.net . Let me ask you a question: “If you wanted to prevent skin cancer would you put SPF 50 in the water supply?” Of course not, the action of SPF 50 is topical. So too is the action of Fluoride. It’s also a very potent toxin that you don’t want taken internally. Have you ever looked at the warnings on a tube of fluoridated toothpaste? There’s enough Fl in one tube to kill a child. Let’s start thinking in terms of proper diet and nutrition, and the education of those parents who don’t do anything to prevent decay in their children because they’re “entitled” to free dental care. My feeling is DYFUS should be called. These parents are significantly abusing their children.
Steve Markus
The Centre for Dentistry at Haddon
209 White Horse Pike
Haddon Heights, NJ 08035
856 546 0665

World Health Organization and Amalgam/Mercury

March 4th, 2010 Comments Off

Interview: ‘WHO can hardly ignore the decision to negotiate a mercury treaty’
by Daniel Zimmermann, DTI

Recently, an agreement in concept was reached by a World Health Organization convened international expert group meeting, supporting the phase-out of dental mercury use worldwide. Dental Tribune Group Editor Daniel Zimmermann spoke with Prof. Lars Hylander, Associate Professor at the University of Uppsala in Sweden who attended the meeting, about the agreement and strategies for future biomaterials use in dentistry.

Daniel Zimmermann: Prof. Hylander, you recently attended a joint meeting of the World Health Organization (WHO) and the United Nations Environment Programme (UNEP) that aimed to assess the latest clinical evidence on dental restorative materials. Could you tell us about the outcome of this meeting?

Prof. Lars Hylander: Most participants agreed that amalgam should be phased out or at least phased down. Dr Poul Erik Petersen, Responsible Officer for Oral Health at the WHO, however, raised several good questions, such as what to tell people in poor countries who cannot even afford dental amalgam fillings. At this point, the room grew rather silent.
A similar consultation was held more in Geneva than ten years ago. What has changed since then
concerning the manner in which dental restorative materials are perceived?

Allergic reactions from amalgam fillings in some patients have been acknowledged by proamalgamists.

Mercury leakages and emissions from dental amalgam into the environment have been fully acknowledged, particularly after dental amalgam was banned in Norway and Sweden, and restricted in Denmark and other places. Proof of methylmercury formation in wastewater from dental clinics is a third factor that makes the continued use of amalgam less justified. Another factor is that alternative tooth filling materials are now available or in development.

What has been decided regarding dental amalgam?
The WHO has not been as quick as Norway, who instituted a ban on dental amalgam in less than six months after the proposal of a ban was presented in the country. Thus far, nothing has been decided, but the WHO can hardly ignore the decision made by the world’s governments within the UNEP to negotiate a mercury treaty, which will begin in Stockholm next June. There was some consensus that mercury use in dentistry should be phased down. A suitable way to do this is to begin teaching alternative restoration techniques, other than dental amalgam, in dental schools.

There was a focus on the oral cavity, which thus ignored the environmental aspects such as mercury emissions from crematoria and leakage of mercury into wastewater from dental clinics and the wearing of amalgam surfaces due to everyday chewing. The American Dental Association demonstrated this most clearly in the presentation by Dr Daniel Meyer, in which it was stated that of the 35 tons of amalgam used annually in the US, only a few hundred kilograms are emitted into the environment.
Which restorative materials were considered to have the most potential for use in developed and developing countries?
Composites and other white filling materials have replaced amalgam in several developed nations. Even in countries without any ban, such as in Japan, less than 4 per cent of the fillings are now fabricated with amalgam, for aesthetic reasons. In addition, many patients do not find it sensible to have as toxic an element as mercury just a few centimetres from their brains.

Composites and glass ionomers are also widely used in many developing countries. The question of why such developments progress so slowly in the big nations of the rich world was raised. Atraumatic restorative treatment with glass ionomers and using only hand tools is a promising alternative, not only for developing countries. In countries in which glass ionomers or composites are produced locally, the cost of these fillings is lower than that of amalgam.
Thank you very much for the interview.

Press Release, Feb 24, 2010
From: Dr. Steve Markus, Haddon Heights, NJ
856 546 0665

Below, is the letter I have written to PA Attorney General, Thomas Corbett with respect to the fact that both the Pennsylvania and Philadelphia County Dental Associations are recommending that the parents of disabled children be strong-armed into accepting fillings with the neuro-toxin, mercury (otherwise known as dental amalgam) or be forced to take their children elsewhere. The research of Vimy, in the 1980’s proved that mercury in dental fillings is not inert, and, in fact, distributes to all organ systems of the body. I am sure you will agree that the disabled need no further health problems, especially neurologic issues iatrogenically induced by the dental profession. Since there is no evidence to prove mercury fillings are safe, shouldn’t we all be erring on the side of caution, rather than promoting a material that has a tainted history going back to its introduction, more than a century and a half ago? Please note, that the information below my signature was copied and pasted. There is a mistake which I could not correct for some reason. Please be aware that the word amalgam in the first sentence of the third paragraph should have read “composite” fillings.

Dear Mr. Corbett:

As a 1975 graduate of the University of Pennsylvania, and a former licensee of the Keystone state, and a keynote speaker before the FDA panel on the toxicity of Hg in dental fillings in 2006, I am astounded at the level of ignorance the message below conveys. Mercury fillings were initially rejected, in the 1850’s by practicing dentists. The technique was adopted by blacksmiths, barbers and jewelers (who the professionals coined the term QUACKs for — the procedure, developed in Germany where mercury = quaksolder) who formed what was the precursor of the ADA. Those with any training in toxicology would know that Hg caused “Mad Hatters’ Disease” – a neurologic disorder. They knew it in 1850! I have been placing composite fillings exclusively since 1990, and see no reason anyone should be arguing in favor of a neurotoxic material for which there are better options. I invite you to open a dialogue, if you are indeed interested in the rights of the citizens of your state, so that bargain-driven and insurance-driven treatment decisions are not relegated to the derision that the tenor of the message below conveys. A copy of this has been released to all local newspapers.
Steve Markus
The Centre for Dentistry at Haddon
www.SmileSouthJersey.com
www.Cent4Dent.com
www.TheEdgeSmiles.com
www.mercurysafedentistrynj.com
www.SymphonicSmiles.com

http://www.sedationdentistnewjersey.com/

http://www.cosmeticdentistrysouthjersey.com/

209 White Horse Pike
Haddon Heights, NJ 08035
856 546 0665

—–

In an act of moral depravity, the Pennsylvania Dental Association (PDA) and the Philadelphia County Dental Society (PCDS) have endorsed strong-arming parents of children with disabilities to force their written consent to mercury fillings. These dental societies issued a statement to the Philadelphia Board of Health dated February 11 giving their stamp of approval to dentists who deny all treatment to disabled children — no tooth cleanings, no preventive care, nothing — unless the parents “consent” to exposing their children to mercury. In the words of the PDA/PCDS representative before the Board of Health, “if a guardian refuses amalgam…we will not see the patient.”

Acknowledging that not having routine dental care is detrimental to health, the PDA/PCDS witness cruelly added that people with disabilities in Philadelphia have no feasible alternative to his amalgam-happy practice: Finding another dental facility equipped to treat people with disabilities would be “a challenge,” he sneered. So the PDA and the PCDS are forcing parents of children with disabilities — even children who already have neurological disorders — to choose: either “consent” to the implantation of a neurotoxin an inch from your child’s brain or no dentist will even clean your child’s teeth.

The PDA and the PCDS know very well that dentists have been successfully placing amalgam in children with disabilities — even under sedation — for years. Both Dr. Chester L. Yokoyama, former Member of the Dental Board of California, and Dr. Blanche Grube, vice president of the International Academy of Biological Dentistry and Medicine, have advised that resin definitely can be used on sedated children. Hence, if these PDA/PCDS dentists can’t implant any filling but this primitive pre-Civil War device, it’s time for them to go get training! And even if PDA/PCDS dentists are too untrained to place non-mercury fillings, what’s their excuse for denying children with disabilities the basic dental cleanings that would prevent cavities in the first place?

Since the PDA and the PCDS claim to support able-bodied persons’ right to choose non-mercury filling materials while announcing support for forcing the disabled to get mercury fillings, we have asked the Attorney General of Pennsylvania to conduct a civil rights investigation, reprinted below. Plain and simple, the sixth-largest chapter of the American Dental Association apparently endorses discrimination against the disabled. (Similar conduct by a North Carolina clinic has already been brought to our attention.)

My friends, now I need your help:

1. Pennsylvanians: If you live or work in the Keystone state, or have family ties there, or your organization has a presence there, please write or email PA Attorney General Thomas Corbett:

Email: civilrights@attorneygeneral.gov
Mailing Address: 16th Floor, Strawberry Square, Harrisburg, PA 17120
Fax: 717-787-8242

Ask the Attorney General to conduct a civil rights investigation into this despicable policy of the Pennsylvania Dental Association and the Philadelphia County Dental Society. Explain to him that every parent needs the right to choose non-mercury dental fillings because mercury is a neurological risk, especially for children who already have neurological problems. If you are a person with a disability or the parent of a child with a disability, explain why it is important for you to have the right to make your own health care decisions and particularly why it is important to be able to choose non-mercury dental fillings. If you share my outrage that these dental trade groups would strong-arm parents into submitting to mercury by threatening not to provide any dental care at all, tell him.

2. Dentists and other dental professionals: Please write PA Attorney General Thomas Corbett (contact info above). Explain that sedated children and children with disabilities can and do get composites. Tell him that the PDA/PCDS policy’s goal is quick & easy profits for dentists, because amalgam is a “drill, fill, and bill” material.

Charlie Brown
24 February 2010

Charles G. Brown, National Counsel
Consumers for Dental Choice
316 F St., N.E., Suite 210, Washington, DC 20002
Ph. 202.544-6333; fax 202.544-6331
charlie@toxicteeth.org, www.toxicteeth.org
Working for Mercury-Free Dentistry

Here’s our request for a civil rights investigation …

Discrimination: PDA and PDCS endorse the denial of all dental treatment
to children with disabilities if parents exercise their right to refuse
mercury fillings, whereas these trade associations permit able-bodied patients to choose non-mercury filling materials

The Pennsylvania Dental Association (PDA) and Philadelphia County Dental Society (PCDS) have endorsed a campaign to force persons with disabilities to submit to mercury amalgam instead of offering them a choice of filling materials — a choice both trade associations openly permit for able-bodied persons.

I. PDA and PCDS promote able-bodied people’s right to make their own health decisions

Everyone is in seeming agreement that individuals have a right to make their own decisions about their bodies, especially decisions affecting their health. In dentistry, this means the right of patients to choose which filling material is implanted into their bodies. PDA and PCDS agree, overtly advocating the patient’s right to choose on their websites: “Many factors may affect your choice of filling material” and “This fact sheet outlines the alternatives available and will help you decide on the right choice for you.” The PCDS even boasted that it “worked hard” to ensure that patients would be presented with all their filling material options.

Increasingly, consumers are exercising their right to refuse dental amalgam, a primitive pre-Civil War filling material containing 50% mercury — a known neurotoxin. In addition to numerous studies indicating that amalgam can cause a wide range of health problems, the U.S. Food and Drug Administration has recently issued warnings making clear that amalgam is a neurological risk at least for children and unborn children:

“Dental amalgam also releases low levels of mercury vapor … The developing neurological systems in fetuses and young children may be more sensitive to the neurotoxic effects of mercury vapor. Very limited to no clinical information is available regarding long-term health outcomes in pregnant women and their developing fetuses, and children under the age of six, including infants who are breastfed.”

Although FDA concealed this warning from consumers in a special controls document labeled in bold “Guidance for Industry and FDA Staff,” the City of Philadelphia prudently decided to inform the public about amalgam with a required information sheet describing these neurological risks and the inconclusiveness of scientific evidence.

Armed with this knowledge, consumers are deciding that they do not want mercury in their bodies or the developing brains of their children. As evidenced by their statements, the PDA and PCDS are respecting the decisions of able-bodied consumers.

II. PDA and PCDS deny people with disabilities their right to make their own health decisions

While able-bodied people are permitted to choose the material being implanted into their bodies, PDA and PCDS advocate a very different standard for people with disabilities. In their joint written testimony, submitted to the Philadelphia Board of Health on 11 February 2010 and presented at the board’s meeting on 18 February 2010, PDA and PCDS endorse the policy of Special Smiles LTD, a North Philadelphia clinic that denies all dental treatment to children with disabilities unless their parents sign a statement consenting to the implantation of mercury amalgam in their children.

This policy abolishes the rights of these parents who do not want a known neurotoxin implanted so near the brains of their children, many of whom already have some form of neurological impairment. They are faced not with the choice presented to able-bodied patients — who are free to reject amalgam and still receive preventative treatments and alternative filling materials — but with a cruel Hobson’s choice: either the dentist will insist on subjecting your child to mercury’s risks or he will refuse to so much as clean your child’s teeth.

With “so few facilities” equipped to treat people with disabilities, there may be no other clinic for parents to turn to for this basic dental care that would prevent many of their children’s cavities in the first place (“Remember! Continuous Care Maintains Good Oral Health” taunts the Special Smiles website). Boasting that he has the economic power to force amalgam onto non-consenting patients in North Philadelphia, Dr. Andrew Mramor of Special Smiles acknowledges that finding dental care for children with disabilities after he expels the family is a “challenge.”

III. Dentists are able to provide people with disabilities the mercury-free dental care afforded to the able-bodied, but PDA and PCDS are unwilling to protect this same option for people with disabilities — and promote punishing those who try to exercise their right to make their own health decisions

Nor can PDA and PCDS justify this policy with the implausible claim that their dentists are unable to place alternative filling materials in children with disabilities. Not only have dentists regularly been using non-amalgam fillings for patients with disabilities — even under sedation — for years, but PDA and PCDS advocate denying people with disabilities all dental care as a punishment for exercising their right to make their own health decisions.

The experiences of dentists confirm that any claim that amalgam is the only option for a sedated child with disabilities is patently false. Dr. Chester L. Yokoyama is a former Member of the Dental Board of California and co-founder and former director of Aiding the Medically Compromised, Inc., a non-profit organization established to promote awareness of dental issues for persons with disabilities. Having spent ten years as a dentist treating children with disabilities in the operating room, Dr. Yokoyama clarifies the situation: “Composites can be done under general anesthesia or IV sedation. If the dentist is unwilling to provide composites for children with disabilities, it raises questions about denying such children access to dental treatment. If the dentist is unable to provide composites for children with disabilities, then he or she can seek further training.” Right here in Pennsylvania, Dr. Blanche Grube, a dentist practicing in Scranton, explains,

“We do composites on children who are sedated, and they work. A study shows the difference between the wear on composites and amalgams is negligible. Dentists placing amalgam make more money — they make more per chair per day, because they can rush through doing amalgam without heed to the toxin questions.”

Regardless of whether their dentists have been trained to place alternative filling materials in sedated patients with disabilities, PDA and PCDS have no excuse to advocate denying all dental care — even teeth cleanings — to people with disabilities who object to mercury. To turn them away, knowing that they will have great difficulty finding another dental clinic equipped to perform sedation dentistry on people with disabilities, effectively deprives them of even the basic dental hygienic care that would prevent tooth decay in the first place! This denial of all dental treatment is clearly intended to punish people with disabilities who dared to exercise their right to choose the filling material going into their mouths — the same right PDA and PCDS insist upon for the able-bodied.

IV. Conclusion

The PDA and PCDS are advocating a policy of discrimination against the disabled, going so far as to commend publicly dentists who refuse to treat children with disabilities. The inadequate training of some dentists must not overshadow the patent bad faith of a cabal determined to strong-arm the disabled into submitting to this toxic 19th century relic. A state dental association and a county dental society in the Commonwealth have selected children with disabilities and their parents — already facing so many problems — for this cruel ultimatum: mercury fillings or no dental care at all.

(signed in hard copy mailed to you)
Charles G. Brown
National Counsel
charlie@toxicteeth.org
23 February 2010

WAKEFIELD DEFENDED

February 24th, 2010 Comments Off

FROM DR. TEN PENNY = Dr. Wakefield has never been “anti-vaccine.” His work has always been focused on finding an explanation for WHY so many autistic children have terrible bowel disease.

Dr. Wakefield has always recommended single antigen vaccines. He hypothesized that the three live viruses given together in the MMR vaccine are the source of potential problems in at least SOME children.

Learn more: http://www.cent4dent.com/html/mercury_issues/vaccines.html
Read the whole article: http://drtenpenny.com/Wakefield_Inquisitioners_Have_their_day.aspx

by Daniel Zimmermann, DTI
Recently, an agreement in concept was reached by a World Health Organization convened international expert group meeting, supporting the phase-out of dental mercury use worldwide. Dental Tribune Group Editor Daniel Zimmermann spoke with Prof. Lars Hylander, Associate Professor at the University of Uppsala in Sweden who attended the meeting, about the agreement and strategies for future biomaterials use in dentistry.
Daniel Zimmermann: Prof. Hylander, you recently attended a joint meeting of the World Health Organization (WHO) and the United Nations Environment Programme (UNEP) that aimed to assess the latest clinical evidence on dental restorative materials. Could you tell us about the outcome of this meeting?
Prof. Lars Hylander: Most participants agreed that amalgam should be phased out or at least phased down. Dr Poul Erik Petersen, Responsible Officer for Oral Health at the WHO, however, raised several good questions, such as what to tell people in poor countries who cannot even afford dental amalgam fillings. At this point, the room grew rather silent.
A similar consultation was held more in Geneva than ten years ago. What has changed since then
concerning the manner in which dental restorative materials are perceived?
Allergic reactions from amalgam fillings in some patients have been acknowledged by proamalgamists.
Mercury leakages and emissions from dental amalgam into the environment have been fully acknowledged, particularly after dental amalgam was banned in Norway and Sweden, and restricted in Denmark and other places. Proof of methylmercury formation in wastewater from dental clinics is a third factor that makes the continued use of amalgam less justified. Another factor is that alternative tooth filling materials are now available or in development.
What has been decided regarding dental amalgam?
The WHO has not been as quick as Norway, who instituted a ban on dental amalgam in less than six months after the proposal of a ban was presented in the country. Thus far, nothing has been decided, but the WHO can hardly ignore the decision made by the world’s governments within the UNEP to negotiate a mercury treaty, which will begin in Stockholm next June. There was some consensus that mercury use in dentistry should be phased down. A suitable way to do this is to begin teaching alternative restoration techniques, other than dental amalgam, in dental schools.

There was a focus on the oral cavity, which thus ignored the environmental aspects such as mercury emissions from crematoria and leakage of mercury into wastewater from dental clinics and the wearing of amalgam surfaces due to everyday chewing. The American Dental Association demonstrated this most clearly in the presentation by Dr Daniel Meyer, in which it was stated that of the 35 tons of amalgam used annually in the US, only a few hundred kilograms are emitted into the environment.
Which restorative materials were considered to have the most potential for use in developed and developing countries?
Composites and other white filling materials have replaced amalgam in several developed nations. Even in countries without any ban, such as in Japan, less than 4 per cent of the fillings are now fabricated with amalgam, for aesthetic reasons. In addition, many patients do not find it sensible to have as toxic an element as mercury just a few centimetres from their brains.

Composites and glass ionomers are also widely used in many developing countries. The question of why such developments progress so slowly in the big nations of the rich world was raised. Atraumatic restorative treatment with glass ionomers and using only hand tools is a promising alternative, not only for developing countries. In countries in which glass ionomers or composites are produced locally, the cost of these fillings is lower than that of amalgam.
Thank you very much for the interview.

For further information visit our mercury issues section.

Tuberous Sclerosis Complex (TSC) and Autism

January 17th, 2010 Comments Off

ScienceDaily (Jan. 11, 2010) — Studying a rare disorder known as tuberous sclerosis complex (TSC), researchers at Children’s Hospital Boston add to a growing body of evidence suggesting that autism spectrum disorders, which affect 25 to 50 percent of TSC patients, result from a miswiring of connections in the developing brain, leading to improper information flow. The finding may also help explain why many people with TSC have seizures and intellectual disabilities.

Findings were published online in Nature Neuroscience on January 10.

TSC causes benign tumors throughout the body, including the brain. But patients with TSC may have autism, epilepsy or intellectual disabilities even in the absence of these growths. Now, researchers led by Mustafa Sahin, MD, PhD, of Children’s Department of Neurology, provide evidence that mutations in one of the TSC’s causative genes, known as TSC2, prevent growing nerve fibers (axons) from finding their proper destinations in the developing brain.

Studying a well-characterized axon route — between the eye’s retina and the visual area of the brain — Sahin and colleagues showed that when mouse neurons were deficient in TSC2, their axons failed to land in the right places. Further investigation showed that the axons’ tips, known as “growth cones,” did not respond to navigation cues from a group of molecules called ephrins. “Normally ephrins cause growth cones to collapse in neurons, but in tuberous sclerosis the axons don’t heed these repulsive cues, so keep growing,” says Sahin, the study’s senior investigator.

Additional experiments indicated that the loss of responsiveness to ephrin signals resulted from activation of a molecular pathway called mTOR, whose activity increased when neurons were deficient in TSC2. Axon tracing in the mice showed that many axons originating in the retina were not mapping to the expected part of the brain.

Although the study looked only at retinal connections to the brain, the researchers believe their findings may have general relevance for the organization of the developing brain. Scientists speculate that in autism, wiring may be abnormal in the areas of the brain involved in social cognition.
“People have started to look at autism as a developmental disconnection syndrome — there are either too many connections or too few connections between different parts of the brain,” says Sahin. “In the mouse models, we’re seeing an exuberance of connections, consistent with the idea that autism may involve a sensory overload, and/or a lack of filtering of information.”

Sahin hopes that the brain’s miswiring can be corrected by drugs targeting the molecular pathways that cause it. The mTOR pathway is emerging as central to various kinds of axon abnormalities, and drugs inhibiting mTOR has already been approved by the FDA. For example, one mTOR inhibitor, rapamycin, is currently used mainly to prevent organ rejection in transplant patients, and Sahin plans to launch a clinical trial of a rapamycin-like drug in approximately 50 patients with TSC later this year, to see if the drug improves neurocognition, autism and seizures.

In 2008, Sahin and colleagues published related research in Genes & Development showing that when TSC1 and TSC2 are inactivated, brain cells grow more than one axon — an abnormal configuration that exacerbates abnormal brain connectivity. The mTOR pathway was, again, shown to be involved, and when it was inhibited with rapamycin, neurons grew normally, sprouting just one axon.

Supporting the mouse data, a study by Sahin and his colleague Simon Warfield, PhD, in the Computational Radiology Laboratory at Children’s, examined the brains of 10 patients with TSC, 7 of whom also had autism or developmental delay, and 6 unaffected controls. Using an advanced kind of MRI imaging called diffusion tensor imaging, they documented disorganized and structurally abnormal tracts of axons in the TSC group, particularly in the visual and social cognition areas of the brain (see image). The axons also were poorly myelinated — their fatty coating, which helps axons conduct electrical signals, was compromised. (In other studies, done in collaboration with David Kwiatkowski at Brigham and Women’s Hospital, giving rapamycin normalized myelination in mice.)

Sahin has also been studying additional genes previously found to be deleted or duplicated in patients with autism, and finding that deletion of some of them causes neurons to produce multiple axons — an abnormality that, again, appears to be reversed with rapamycin.

“Many of the genes implicated in autism may possibly converge on a few common pathways controlling the wiring of nerve cells,” says Sahin. “Rare genetic disorders like TSC are providing us with vital clues about brain mechanisms leading to autism spectrum disorders. Understanding the neurobiology of these disorders is likely to lead to new treatment options not only for TSC patients, but also for patients with other neurodevelopmental diseases caused by defective myelination and connectivity, such as autism, epilepsy and intellectual disability.”

The current study was funded by grants from the National Institutes of Health, the John Merck Scholars Fund, Tuberous Sclerosis Alliance, the Manton Foundation, the Children’s Hospital Boston Translational Research Program, and the Children’s Hospital Boston Mental Retardation and Developmental Disabilities Research Center.

Duyu Nie was first author on the paper. Coauthors were Duyu Nie, Alessia Di Nardo, Juliette M Han, Hasani Baharanyi, Ioannis Kramvis, and ThanhThao Huynh, all of the F.M. Kirby Neurobiology Center and Department of Neurology, Children’s Hospital Boston; Sandra Dabora of Brigham and Women’s Hospital; Simone Codeluppi and Elena B Pasquale of the Burnham Institute for Medical Research, and University of California San Diego; and Pier Paolo Pandolfi of Beth Israel Deaconess Cancer Center.

For more info, look at the Mercury and Autism pages of My Website.

There are no published studies, no records of any clinical trials, and no publicly-available paper trail demonstrating that any safety testing was done whatsoever. There is no researcher who has publicly put their name on the record declaring the vaccines to be safe, and no FDA official has ever stated that scientifically-valid safety testing has ever been conducted on the vaccine / adjuvant combinations now being distributed across America.
Normally, when a pharmaceutical achieves “FDA approved” status, there is a considerable paper trail of scientific scrutiny, peer review, clinical trials and other supporting evidence. Read more:

MY PAIN IS FINALLY GONE!

December 15th, 2009 Comments Off

For three years I have been dealing with pain and headaches related to TMJ dysfunction. I have been to countless MD’s and Dentists. After a consultation, Dr. Markus fabricated an NTI-tss device to control my night time clenching and grinding. He also made some adjustments to my bite, after using a very cool device called the Tekscan which measures bite pressure and equilibrium. My first visit was in August 09 and by late September my pain had reduced by half. By November I was virtually pain free! As evidenced by the above, I believe Dr. Markus has the ability to diagnose and treat the most complex joint in the body, the temporomandibular joint. Thanks!
-Scott