2. Many chronic systemic diseases that we thought we knew the causes for, now are thought to be the result of bacteria or viruses. One speaker suggested that today, probably 20% of cancers were generally attributed to viral attack, but he thought in five years that would probably be 50%. Just think, half of all cancers caused by viruses! One of great concern today is the HPV, or human papilloma virus, which is the cause of much cervical cancer, and many oral cancers today in young people. But research is also showing us relationships between oral infections and heart disease, diabetes, and stroke incidence!

3. Today, we can test your mouth earlier with a painless bacterial DNA test to see which bacteria are there, and also what the relative bacterial load is there for that species. That will tell the dentist what antibiotic to use and what treatment regimen would be most likely to work.

Dentistry has been really guilty of ignoring this disease, and often not treating it until actual bone damage had occurred. Today, we are focusing on full time health, prevention of early disease, and the systemic health that occurs when someone is infection free.

If you have any question about this, please don’t hesitate to call and ask for our help. 903-581-1777.

Here is what to look for with periodontal health:
1. Gums that bleed – anytime. Just like the skin on your hand, your gums shouldn’t bleed when you brush or floss. Ever.
2. Persistant bad breath. It is an infection, and you know how that can smell!
3. A bad taste in your mouth- also the result of an infection.
4. Loose teeth are a bad sign, that means that bone has been lost and it is awfully difficult to get it back, if it is possible at all.

For more information, visit here.

A second study by the same team of researchers found that people age 50 or older who lack vitamin D are at a higher risk for heart disease and stroke, and are more likely to die earlier than people the same age who get adequate amounts of the vitamin.

excerpted from: Health.com
By Denise Mann
November 16, 2009 4:56 p.m. EST

Read the whole article: click

A service of Dr. Markus

More information:
The results of a study presented on November 16, 2009 at the American Heart Association’s Scientific Conference in Orlando, Florida, confirmed a strong association between the presence of reduced vitamin D levels and a greater risk of coronary artery disease, stroke, heart failure and dying over follow-up in men and women 50 years of age and older.

Brent Muhlestein, MD and his colleagues at Intermountain Medical Center in Salt Lake City followed 27,686 subjects with no history of heart disease for an average of 1.2 years. Serum 25-hydroxyvitamin D levels obtained during routine clinical care were classified as normal at over 30 nanograms per milliliter (ng/mL), low at between 15 to 30 ng/mL or very low at less than 15 ng/mL.

Over the follow-up period, 2,614 participants developed coronary artery disease, 1,742 developed heart failure, 314 experienced a stroke and 1,193 deaths occurred. Those with very low vitamin D levels were 45 percent likelier to develop heart disease, twice as likely to develop heart failure, 78 percent more likely to experience a stroke,and 77 percent likelier to die than those with normal levels. Subjects whose vitamin D levels were classified as “low” as opposed to “very low” also had greater risks of these conditions, however, the increase compared to those with normal levels was not as great as the very low group.

“This was a unique study because the association between Vitamin D deficiency and cardiovascular disease has not been well-established,” commented Dr Muhlestein, who is the director of cardiovascular research of Intermountain Medical Center’s Heart Institute. “Its conclusions about how we can prevent disease and provide treatment may ultimately help us save more lives.”

“Utah’s population gave us a unique pool of patients whose health histories are different than patients in previous studies,” he remarked. “For example, because of Utah’s low use of tobacco and alcohol, we were able to narrow the focus of the study to the effects of vitamin D on the cardiovascular system.”

“We concluded that among patients 50 years of age or older, even a moderate deficiency of Vitamin D levels was associated with developing coronary artery disease, heart failure, stroke, and death,” noted coauthor Heidi May, PhD, MS, who is an epidemiologist with the Intermountain Medical Center research team. “This is important because vitamin D deficiency is easily treated. If increasing levels of vitamin D can decrease some risk associated with these cardiovascular diseases, it could have a significant public health impact. When you consider that cardiovascular disease is the leading cause of death in America, you understand how this research can help improve the length and quality of people’s lives.”

“We believe the findings are important enough to now justify randomized treatment trials of supplementation in patients with Vitamin D deficiency to determine for sure whether it can reduce the risk of heart disease,” Dr Muhlestein added.

OBJECTIVE: Microbial biofilms are communities of sessile microorganisms formed by cells that are attached irreversibly to a substratum or interface or to each other and embedded in a hydrated matrix of extracellular polymeric substances. Microbial biofilms have been implicated in >80% of human infections such as periodontitis, urethritis, endocarditis, and device-associated infections. Thus far, intraamniotic infection has been attributed to planktonic (free-floating) bacteria. A case is presented in which “amniotic fluid sludge” was found to contain microbial biofilms. This represents the first report of a microbial biofilm in the amniotic cavity.

STUDY DESIGN: “Amniotic fluid sludge” was detected by transvaginal sonography and retrieved by transvaginal amniotomy. Bacteria were identified with scanning electron microscopy and fluorescence in situ hybridization for conserved regions of the microbial genome; the exopolymeric matrix was identified by histochemistry by the wheat germ agglutinin lectin method. The structure of the biofilm was imaged with confocal laser scanning microscopy.

RESULTS: “Amniotic fluid sludge” was imaged with scanning electron microscopy, which allowed the identification of bacteria embedded in an amorphous material and inflammatory cells. Bacteria were demonstrated with fluorescent in situ hybridization using a eubacteria probe. Extracellular matrix was identified with the wheat germ agglutinin lectin stain. Confocal microscopy allowed 3-dimensional visualization of the microbial biofilm.

CONCLUSION: Microbial biofilms have been identified in a case of intraamniotic infection with “amniotic fluid sludge.”

IMPLICATION: Periodontal infections cross the placenta and infect the fetus

Further information about gum disease and your health, click here:

A major research grant will help scientists study the links between memory and
oral health in a bid to establish control over Alzheimer’s disease. The news of
a $1.3 million study to be carried out on thousands of participants has been
welcomed by the UK’s leading oral health charity – the British Dental Health
Foundation.

Research has long associated oral health with overall health problems,
including dementia – though no studies have made clear how the state of the
teeth and mouth affect mental function.

Last year researchers found a link between mild memory loss and gum disease*
and the seven-figure grant will enable examination of medical records of
thousands of Americans to further pursue the link.

Foundation chief executive Dr Nigel Carter welcomed the news saying: “Oral
health and gum disease in particular has been increasingly linked to overall
health through studies such as this exciting piece of research.

“The recent review of NHS dentistry suggested the government is committed to
preventive care.

“It would be a great boost if scientists could prove preventive treatment could
not only protect our teeth but also help prevent chronic diseases such as
Alzheimer’s. “We will watch developments with interest and urge the public to
make sure they look after their oral health with simple steps which can reduce
the risk of gum disease. “Minimising the risks caused by poor oral hygiene is
as simple as brushing teeth twice a day with a fluoride toothpaste and visiting
the dentist regularly for professional check-ups.”

The US studies will be led by Dr Bei Wu of the University of North Carolina and
Dr Richard Crout of the University of West Virginia, who will continue with a
program testing oral health and memory in 273 people aged 70.

The new funding will establish larger studies looking for links between oral
health and brain function over time, while scientists will also seek to
establish a link between improved cognitive function and better oral hygiene
through intervention to improve oral health.

In an interview this week Dr Crout, who has predicted that dentists may in
future be in a position to administer memory tests on older patients, said: “to
have overall good general health you need to have good oral health.”

Source
The British Dental Health Foundation

Article URL: http://www.medicalnewstoday.com/articles/158118.php

For further information, please read the Floss or Die pages of our website.

CHICAGO, Illinois–Cardiovascular disease, the leading killer in the United States, is a major public health issue that contributes to 2,400 deaths each day.

Periodontal disease, a chronic inflammatory disease that destroys the bone and tissues that support the teeth, affects nearly 75 percent of Americans and is the major cause of adult tooth loss. While the prevalence rates of these disease states seem grim, research suggests that managing one disease may reduce the risk for the other.

A consensus paper on the relationship between heart disease and gum disease was recently developed by the American Academy of Periodontology and The American Journal of Cardiology. The paper is published concurrently in the online versions of the AJC, a peer-reviewed journal circulated to 30,000 cardiologists, and the Journal of Periodontology, the official publication of the AAP.

Developed in concert by cardiologists and periodontists, the paper includes clinical recommendations for medical and dental professionals to use in managing patients living with, or who are at risk for, either disease. As a result of the paper, cardiologists may now examine a patient’s mouth, and periodontists may begin asking questions about heart health and family history of heart disease.

Specific clinical recommendations include:

* Patients with periodontitis who have one known major atherosclerotic CVD risk factor such as smoking, immediate family history for CVD, or history of dyslipidemia should consider a medical evaluation if they have not done so within the past 12 months.

* A periodontal evaluation should be considered in patients with atherosclerotic CVD who have: signs or symptoms of gingival disease, significant tooth loss, and unexplained elevation of hs-CRP or other inflammatory biomarkers.

* A periodontal evaluation of patients with atherosclerotic CVD should include a comprehensive examination of periodontal tissues, as assessed by visual signs of inflammation and bleeding on probing, loss of connective tissue attachment detected by periodontal probing measurements, and bone loss assessed radiographically. If patients have untreated or uncontrolled periodontitis, they should be treated with a focus on reducing and controlling the bacterial accumulations and eliminating inflammation.

* When periodontitis is newly diagnosed in patients with atherosclerotic CVD, periodontists and physicians managing patients’ CVD should closely collaborate in order to optimize CVD risk reduction and periodontal care.

The clinical recommendations were developed at a meeting held in early 2009 of top opinion leaders in cardiology and periodontology. The consensus paper also summarizes the scientific evidence that links periodontal disease and cardiovascular disease and explains the underlying biologic and inflammatory mechanisms that may be the basis for the connection.

According to Kenneth Kornman, DDS, PhD, editor of the Journal of Periodontology and a co-author of the consensus report, the cooperation between the cardiology and periodontal communities is an important first step in helping patients reduce their risk of these associated diseases.

“Inflammation is a major risk factor for heart disease, and periodontal disease may increase the inflammation level throughout the body,” Dr. Kornman said. “Since several studies have shown that patients with periodontal disease have an increased risk for cardiovascular disease, we felt it was important to develop clinical recommendations for our respective specialties. Therefore, you will now see cardiologists and periodontists joining forces to help our patients.”

While additional research will help identify the precise relationship between periodontal disease and cardiovascular disease, recent emphasis has been placed on the role of inflammation–the body’s reaction to fight off infection, guard against injury or shield against irritation.

While inflammation initially intends to have a protective effect, untreated chronic inflammation can lead to dysfunction of the affected tissues, and therefore to more severe health complications.

“Both periodontal disease and cardiovascular disease are inflammatory diseases, and inflammation is the common mechanism that connects them,” said Dr. David Cochran, DDS, PhD, president of the AAP and chair of the Department of Periodontics at the University of Texas Health Science Center at San Antonio.

“The clinical recommendations included in the consensus paper will help periodontists and cardiologists control the inflammatory burden in the body as a result of gum disease or heart disease, thereby helping to reduce further disease progression, and ultimately to improve our patients’ overall health. That is our common goal.”

For more information read the Floss or Die pages of our website.

This new study, the first of its kind, specifically looked at pharmaceutical
advertising as compared with journal text about dietary supplements. The
authors reviewed a year’s worth of issues from each of eleven of the largest
medical journals: the Journal of the American Medical Association, New
England Journal of Medicine, British Medical Journal, Canadian Medical
Association Journal, Annals of Internal Medicine, Archives of Internal
Medicine, Archives of Pediatric and Adolescent Medicine, Pediatrics and
Pediatric Research, and American Family Physician.

The results were statistically significant. . . and embarrassing. Medical
journals carrying the most pharmaceutical ads “published significantly fewer
major articles about dietary supplements per issue than journals with the
fewest pharmads (P < 0.01). Journals with the most pharmads published no
clinical trials or cohort studies about supplements. The percentage of major
articles concluding that supplements were unsafe was 4% in journals with
fewest and 67% among those with the most pharmads (P = 0.02)." The authors
concluded that "the impact of advertising on publications" is real, and said
that "the ultimate impact of this bias on professional guidelines, health
care, and health policy is a matter of great public concern."

Indeed it is. Health care costs are rising and drug profits are enormous.
Canadian psychiatrist Abram Hoffer, M.D, Ph.D., says: "We all have to work
hard to educate the public about the merits of sane treatment for everyone,
where the patient is primary, not Big Pharma." Bo H. Jonsson, M.D., Ph.D.,
of the Karolinska Institute in Sweden, comments that "Positive reports about
the effects of high-dose vitamins have long been ignored by the medical
establishment instead of being further examined scientifically."

When patients ask about nutritional treatments, many a family physician has
replied, "I've never seen any studies supporting the safety or efficacy of
vitamin supplements in my professional journals. The research is simply not
there."

Sadly, they are right. And now we know why.

Major medical journals, their editors, and their authors appear to be on the
take. Harsh words? Perhaps, but only because the truth is harsh. "One the
take" refers to receiving cash in exchange for influence. It is naive to
assume that money does not corrupt. Promoting vested interests masquerading
as science is wrong and it must be stopped. At the very least, accepting
money carries an obligation to account for the source of that money. All
medical journals should be compelled to print a full disclosure in every
issue itemizing exactly how much money comes from exactly which sources.

Any medical journal that won't disclose has a reason to not disclose. And
that reason has nothing to do with public health. It's about private cash.
The cash that induces the journals to sway the doctors to persuade the
public.

If the medical journals deny this, let them prove it with full disclosure.
Now.

*References:*
(1) Kemper KJ, Hood KL. Does pharmaceutical advertising affect journal
publication about dietary supplements? BMC Complement Altern Med. 2008 Apr
9;8:11. Full text at

http://www.biomedcentral.com/1472-6882/8/11or

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=18400092

For years we have been advising our patients about the need to take supplements, and feel that organized medicine has let the patients of this country down. Medical Doctors, MD’s, are just that, pushers of pills. To read more look at: http://www.cent4dent.com/pdfs/vaccines_essayLong.pdf and be sure to look at the Floss or Die pages of www.cent4dent.com

aDepartment of Nephrology, Medical Faculty, and
bDepartment of Periodontology, Dental Faculty, University of Dicle, Diyarbakir, Turkey

Address of Corresponding Author

Blood Purif 2006;24:400-404 (DOI: 10.1159/000093683)

——————————————————————————–

Abstract

Aim: To evaluate the association between C-reactive protein (CRP) levels and the periodontal status of hemodialysis (HD) patients. Methods: 41 HD patients on rHuEPO therapy were enrolled in the study. Hematologic and biochemical parameters and CRP levels were recorded. The plaque index, gingival index, probing pocket depth and periodontal disease index were used to identify periodontal disease. The patients were divided into 2 groups: group 1 (n = 21), high CRP, and group 2 (n = 20), normal CRP. Results: After periodontal therapy, while the mean CRP level and erythrocyte sedimentation rate declined from 30.46 to 10.36 (p = 0.001) and from 93.4 to 35.8 mg/l (p = 0.001), respectively, the hemoglobin level increased from 9.4 to 10.6 g/dl (p = 0.009) and hematocrit level from 28.2 to 32.0% (p = 0.008) in group 1. Conclusion: Periodontitis is an important and occult source of chronic inflammation and increases the CRP levels in HD patients. Periodontitis can cause hyporesponsiveness to rHuEPO treatment and decrease the hemoglobin levels.

for further information, visit the “Floss or Die” pages of www.cent4dent.com

There are two DNA-PCR laboratory facilities in the United States that have been approved for nucleic acid testing for periodontal diseases. As a result of the latest DNA research and analyzed by the esteemed periodontal researcher, Dr Ken Kornman, as well as the research performed at Perio Arts Research, (the research division of PAI), I would highly recommend OralDNA Labs, under the direction of Dr. Tom Nabors. I have recently toured their new facility and was highly impressed with the level of technical operations present, as well as the sophistication of the team at OralDNA. Their level of commitment remains second to none. At PAI, independent testing of their bacterial DNA results compared to the other lab’s results indicate a greater sensitivity in diagnosing periodontal pathogens, as well. As their website states, “They are a state-of-the-art oral diagnostics laboratory using gold standard, DNA-PCR technology to accurately determine the bacterial and genetic causes of periodontal infections. Their two diagnostic tests identify causative pathogens, bacterial load, stage of progression and determine who is most susceptible.”

I have no ownership status at OralDNA and PAI nor I have received compensation for our research or this endorsement.

Visit our website www.cent4dent.com and see the Floss or Die Pages, for further information

Founder and Director, Perio Arts Institute www.PerioArtsInstitute.com

SamahaDDS@PWDentalArts.com

About OralDNA Labs, Inc. (http://www.OralDNA.com):

OralDNA Labs, Inc. is a specialty diagnostics company created to advance clinical testing in the dental community. Our goal is to help the dental profession achieve better clinical outcomes by providing reliable, definitive and cost effective clinical tests that drive the detection and prognosis of disease at an earlier, more treatable stage, with an initial focus on periodontal disease.

Periodontal disease is a bacterial infection that causes an inflammatory response. The disease is present in an estimated three quarters of the adult population in the United States, with 30-35% of this population having a genetic trait which predisposes these individuals to more serious forms of the disease. If patients are not properly diagnosed and treated at early stages, periodontal disease can lead to bone loss, tooth loss and implant failure. Research now suggests an increased risk to a number of systemic diseases when chronic periodontal infections are left untreated.

OralDNA offers two DNA-PCR tests for periodontal disease diagnosis and genetic susceptibility. MyPerioPathsm detects the presence and quantity of specific bacteria associated with periodontal disease. MyPerioIDsm PST®, licensed through a marketing, sales and distribution agreement with Interleukin Genetics, provides a means of assessing an individual’s genetic risk for periodontal disease.

The company is also developing an oral HPV test for use in assessing risks associated with oral cancer. Thereafter, OralDNA intends to develop a broader menu of clinical laboratory tests for use in oral medicine.

DNA testing recommendations and OralDNA 109.doc

http://www.cent4dent.com/html/office_info/flossdie.html

We often times take our bodies for granted. And yes, your mouth is part of your body. Why is this important? Just ask me because I had triple bypass surgery ten years ago.

But it wasn’t my mouth that was the culprit, just genetics. But your mouth could be part of some of your health problems like heart disease and diabetes. Here’s how.

Let’s talk about heart disease. We all know one culprit is cholesterol. But what we don’t know is that for cholesterol to affect us we need it to stick to our arterial walls and for that stuff called plaque to form requires INFLAMMATION. Ironically, we also call the build up in our mouth “plaque”. In our arteries it starts out soft, just like in the mouth, then hardens and clogs our arteries. In our mouth it becomes what most people call “tartar”.

So what, I have tartar in my mouth. Well, that stuff is like barnacles on a piling. Bacteria are living in it like fish in a coral reef. Yes, barnacles are full of bacteria. Ask me, I know because I had hand surgery to remove an infection I got cleaning my boat bottom.

Why did my hand swell? I had infection and INFLAMMATION, just like in the mouth. And inflammation is the real culprit in heart disease. You see, cholesterol won’t stick to the wall of your arteries unless there is inflammation, just like in gum disease.

We now have cultured bacteria from the mouth from infected heart arteries. So, if you have inflammation in your mouth from gum disease, chances are you have inflammation in your heart arteries.

Now, about your cholesterol test. The good, the bad, and the ugly. Most are tested for the Good, HDL, the bad, LDL, but not the ugly. The ugly is really ‘uglies” because LDL can be good or bad. The good LDL is a large molecule with low energy and is like a ping pong ball, it bounces off the artery wall, if you will. The bad LDL, is a small,high energy molecule, that penetrates the arterial wall, causing INFLAMMATION, and the formation of plaque that clogs our arteries. The bad LDL is genetic. It’s what I have. But it can be controlled.

The other part of the ugly is INFLAMMATION. Fortunately, we can test for it. It’s called “C-reactive Protein”. There is even a medicine for it called Cerefolin-NAC. That stands for “a folic acid vitamin” plus N-Acetyl Cystein. When my doctor first told me about it she said it has a long name most people never heard of. I said, “Oh, you mean N-Acetyl Cystein”. She said how’d you know? I said , “duh, when I was a body builder ten years ago before my heart surgery, we always took NAC to recover from a hard work out because it reduces INFLAMMATION. I’m glad medicine has caught up with body builders.

Our diabetic patients are amazed when I look in their mouth and tell them their insulin is out of control. How’d you know? Look at your gums, they are swollen, red, and bleeding with that yucky stuff coming out. Yes, gum disease, diabetes, and heart disease are all related.

So why am I writing this article? So you can better understand heart disease, your mouth, and in the hopes you will visit your dentist and find out if you have gum disease and get it treated. You don’t have to have surgery. We treat gum disease with removal of the hard deposits and then with our Laser to help re-grow lost bone. Yes, we get you numb ‘cause it hurts if you are not numb. With the Laser we don’t usually have to numb you.

We offer free gum disease screening exams in our office here in Haddon Heights and hope you are caring for your mouth. Thank you for reading this article and we hope you have a healthy, happy mouth and heart.

This is a letter, written by a friend of mine. For more info, visit

Gary L. Fishbein, D.M.D.

Fellow, Academy General Dentistry

Certified in Laser Dentistry, Academy of Laser Dentistry

Palmetto Creek Dental

Lillian, AL

961-3737